I already have the staff. I grab it after cet killed that guy G'ezzerd or something. I also had a key from Adrianna. I tried killing adrianna and her girls, but they keep wiping me out. Is there a better way to kill adrianna and her girls without getting wiped out? Also, where can I find this magga vampire? is she in the vault? Is she in one of the tunnels? Precise location of this Magga vampire would be appreciated.

With Adrianna, find the scroll of banishing like she asked and hand it over. Then step back to a safe distance. If you still can't cope, just run through and out the back door. They can't follow.

Mada Mabbig is locked in the vault as you guessed. You need the lich's staff to open the door to her room.